University of Iowa Health Care

Ophthalmology and Visual Sciences

Atypical Nevus

19-year-old white female with a history of a stable iris nevus in her right eye since age 2 years. Significant family history: both father and grandfather died of cutaneous melanoma. This iris lesion was stable until July 2002 when it started to enlarge. This baseline video was obtained. In 2007 the lesion was clearly larger. VA 20/20 IOP = 14 mm Hg bilaterally. She underwent enucleation. Pathologic diagnosis: "“Atypical iris nevus, most consistent with borderline spindle cell nevus type. Lesion extends into trabecular meshwork. Satellite lesions are present in the angle.”